ON INTERPRETING THE INHIBITION OF AND CATALYSIS BY DIHYDROFOLATE-REDUCTASE

被引：18

作者：

TAIRA, K

FIERKE, CA

CHEN, JT

JOHNSON, KA

BENKOVIC, SJ

机构：

[1] PENN STATE UNIV,DEPT CHEM,UNIVERSITY PK,PA 16802

[2] PENN STATE UNIV,DEPT BIOCHEM MICROBIOL MOLEC & CELL BIOL,UNIVERSITY PK,PA 16802

[3] DEV CTR BIOTECHNOL,TAIPEI,TAIWAN

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1987年 / 12卷 / 07期

关键词：

D O I：

10.1016/0968-0004(87)90134-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：275 / 278

页数：4

共 19 条

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[14]

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[15]

MATTHEWS DA, 1985, J BIOL CHEM, V260, P381

[16] IDENTIFICATION OF THE H-1 RESONANCES OF VALINE AND LEUCINE RESIDUES IN DIHYDROFOLATE-REDUCTASE BY USING A COMBINATION OF SELECTIVE DEUTERATION AND TWO-DIMENSIONAL CORRELATION SPECTROSCOPY [J].

SEARLE, MS ;

HAMMOND, SJ ;

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ROBERTS, GCK ;

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KING, RW ;

GRIFFITHS, DV .

FEBS LETTERS, 1986, 194 (01) :165-170

[17] MECHANISM OF INHIBITION OF DIHYDROFOLATE REDUCTASES FROM BACTERIAL AND VERTEBRATE SOURCES BY VARIOUS CLASSES OF FOLATE ANALOGS [J].

STONE, SR ;

MORRISON, JF .

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[18]

STONE SR, 1983, BIOCH BIOPHYS ACTA, V75, P247

[19] METHOTREXATE, A HIGH-AFFINITY PSEUDOSUBSTRATE OF DIHYDROFOLATE-REDUCTASE [J].

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MORRISON, JF ;

DUGGLEBY, RG .

BIOCHEMISTRY, 1979, 18 (12) :2567-2573

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