ANTIMICROBIAL POTENTIAL AND SCREENING OF ANTIMICROBIAL COMPOUNDS OF COSTUS IGNEUS USING GC-MS

Medicinal plants have been used as a source of medicine and in widespread use of herbal remedies and healthcare preparations. The present study was conducted to evaluate the antimicrobial potentiality of methanol solvent extracts of mature leaves of Costus igneus against five pathogenic bacterial isolates viz., Escherichia coli, Pseudomonas aeruginosa sp, Klebsiella pneumonia sp, Bacillus subtilis sp, Proteus mirablis sp. The antibacterial potential of Costus igneus methanol extract was tested by using Agar well diffusion method. The methanol extract of Costus igneus (100mg/ml) showed maximum zone of inhibition (7mm) against Escherichia coli sp. where as Proteus mirablis sp showed less zone of inhibition (4mm). The methanol extract of Costus igneus (100mg/ml) showed maximum zone of inhibition (7mm) against Penicillium sp. But Candida albicans sp showed less zone of inhibition (4mm). Phytochemical tests were performed and showed that the antibacterial activity of Costus igneus plant leaves was due to to the presence of phytochemical compounds like alkaloids, terpenoids, tannins, glycosides, and saponins. GC-MS analysis revealed the presence of 20 compounds.