The effect that two methods of root canal obturation, combined with removal of the smear layer, had on coronal leakage was studied in vitro. Single-rooted teeth with mature apices were prepared chemomechanically and divided into two groups of 72 teeth each. One of the groups was treated with 40% citric acid and 2% sodium hypochlorite to remove the smear layer. The teeth were then subdivided and obturated using the glass ionomer sealer, Ketac Endo and either lateral condensation or Thermafil. After storage for 7 days or 4 months, the specimens were evaluated for coronal leakage using Indian ink. After 90 h, each root was split longitudinally and the maximum extent of leakage was measured using a stereomicroscope at x6 magnification. After 7 days, there was significantly less leakage in those teeth obturated with Thermafil without smear layer compared with the other groups (p < 0.05). After 4 months, there was no significant difference in leakage between the groups (p > 0.05).