CEREBROSPINAL-FLUID MONOAMINE METABOLITES AND NEUROPEPTIDES IN PATIENTS WITH PANIC DISORDER

被引:5
|
作者
LEPOLA, U
JOLKKONEN, J
PITKANEN, A
RIEKKINEN, P
RIMON, R
机构
[1] UNIV KUOPIO, DEPT NEUROL, KUOPIO, FINLAND
[2] UNIV HELSINKI, DEPT PSYCHIAT, SF-00100 HELSINKI 10, FINLAND
关键词
CSF; Monoamine metabolites; Neuropeptides; Panic disorder;
D O I
10.3109/07853899009148933
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Concentrations of homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), 3-methoxy-4-hydroxyphenylgycol (MHPG) as well as somatostatin (SRIF) and ßendorphin (ßEND) were assayed in the cerebrospinal fluid (CSF) of 34 patients with panic disorder and of ten neurological controls. No aberrations of the monoaminergic or peptidergic variables measured were found in the nonpanic state of patients with panic disorder. A modest correlation (P == 0.04) between total anxiety scores and CSF MHPG was observed. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:237 / 239
页数:3
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