Etaloning, fluorescence and ambient light suppression by modulated wavelength Raman spectroscopy

被引：20

作者：

Dochow, Sebastian ^{[1
]}

Bergner, Norbert ^{[1
]}

Matthaeus, Christian ^{[1
]}

Praveen, Bavishna B. ^{[2
]}

Ashok, Praveen C. ^{[2
]}

Mazilu, Michael ^{[2
]}

Krafft, Christoph ^{[1
]}

Dholakia, Kishan ^{[2
]}

Popp, Jrgen ^{[1
,3
,4
]}

机构：

[1] Inst Photon Technol, Albert Einstein Str 9, D-07745 Jena, Germany

[2] Univ St Andrews, Sch Phys & Astron, St Andrews, Fife, Scotland

[3] Friedrich Schiller Univ Jena, Inst Phys Chem, Jena, Germany

[4] Friedrich Schiller Univ Jena, Abbe Ctr Photon, Jena, Germany

来源：

BIOMEDICAL SPECTROSCOPY AND IMAGING | 2012年 / 1卷 / 04期

基金：

英国工程与自然科学研究理事会;

关键词：

Raman spectroscopy; shifted excitation; autofluorescence suppression;

D O I：

10.3233/BSI-120031

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

We demonstrate that wavelength modulation overcomes frequent obstacles for in-situ and in-vivo implementations of Raman spectroscopy, namely autofluorescence, removal of the system transmission function including etaloning as well as compensation of ambient light. It is the method of choice for Raman measurements of samples with high background under ambient light conditions such as real-time assessment of tissues in the operating theatre.

引用

页码：383 / 389

页数：7

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