TOXICOLOGICAL EFFECTS OF ZIRAM, THIRAM, AND DITHANE M-45 ASSESSED BY SPERM SHAPE ABNORMALITIES IN MICE

被引:26
作者
HEMAVATHI, E [1 ]
RAHIMAN, MA [1 ]
机构
[1] MANGALORE UNIV,DEPT BIOSCI,MANGALORE,INDIA
来源
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH | 1993年 / 38卷 / 04期
关键词
D O I
10.1080/15287399309531727
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The three commonly used dithiocarbamate fungicides ziram, thiram, and dithane M-45 were investigated for their mutagenic and carcinogenic potency using sperm shape abnormalities in mice. The fungicides were administered intraperitoneally in single and cumulative doses. All three of the fungicides tested were found to induce significant increase in the frequency of abnormal sperm at all the doses, and a linear dose effect was observed.
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页码:393 / 398
页数:6
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