BLOOD-GROUP N-ANTIGEN PRECURSOR GLYCOPROTEINS AND N-ANTIGEN PRECURSOR GLYCOPROTEINS WITH THOMSEN-FRIEDENREICH (T) ACTIVITY FROM HUMAN LIVER METASTATIC CARCINOMAS

被引：0
|
作者：
OTSUKA, K
KUDO, T
NAKAJIMA, T
OHKUMA, S
机构：
[1] TOKYO COLL PHARM,DEPT BIOCHEM,1432-1 HORINOUCHI,HACHIOJI,TOKYO 19203,JAPAN
[2] KAWAGUCHI MUNICPAL HOSP,DEPT SURG,4-5-24 HONCHO,KAWAGUCHI,SAITAMA 332,JAPAN
[3] GUNMA UNIV,SCH MED,DEPT PATHOL 2,MAEBASHI,GUNMA 371,JAPAN
来源：
INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1991年 / 23卷 / 5-6期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1. Four percholoric acid-soluble fractions (PASFs) from human liver metastases of sigmoid colon carcinoma (LSCC), pancreas carcinoma (LPC), breast carcinoma (LBC) and human normal liver (NL) were subjected to DEAE-cellulose column chromatography and separated into three glycoprotein fractions, respectively. 2. In chromatography, LSCC-PASF and LBC-PASF gave Thomsen-Friedenreich (T)-active glycoprotein, blood group N antigen precursor glycoprotein with T activity and N antigen precursor glycoprotein, respectively. 3. LPC-PASF gave N antigen precursor glycoprotein with T activity and two N antigen precursor glycoproteins. 4. The three glycoprotein fractions from NL-PASF did not exhibit both T activity and N antigen precursor activity.
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页码：569 / 578
页数：10
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