PROKARYOTIC GENETIC-CODE

被引：30
|
作者：
OSAWA, S
MUTO, A
OHAMA, T
ANDACHI, Y
TANAKA, R
YAMAO, F
机构：
[1] Laboratory of Molecular Genetics, Department of Biology, School of Science, Nagoya University, Nagoya, 464-01, Chikusa-ku
来源：
EXPERIENTIA | 1990年 / 46卷 / 11-12期
关键词：
GENETIC CODE; DIRECTIONAL MUTATION PRESSURE; GC-CONTENT; UNASSIGNED CODON; TRANSFER RNA; CODON CAPTURE; CODON USAGE; MYCOPLASMA; MITOCHONDRIA; MICROCOCCUS; METHANOGENS;
D O I：
10.1007/BF01936919
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The prokaryotic genetic code has been influenced by directional mutation pressure (GC/AT pressure) that has been exerted on the entire genome. This pressure affects the synonymous codon choice, the amino acid composition of proteins and tRNA anticodons. Unassigned codons would have been produced in bacteria with extremely high GC or AT genomes by deleting certain codons and the corresponding tRNAs. A high AT pressure together with genomic economization led to a change in assignment of the UGA codon, from stop to tryptophan, in Mycoplasma.
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页码：1097 / 1106
页数：10
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