SYNTHESIS OF 3-DIALKYLAMINOCHROMANS VIA THALLIUM(III)-INDUCED CYCLIZATION OF ALLYL ARYL ETHERS

被引：4

作者：

ANDERSSON, B ^{[1
]}

WIKSTROM, H ^{[1
]}

HALLBERG, A ^{[1
]}

机构：

[1] UNIV LUND,CTR CHEM,DEPT ORGAN CHEM 1,S-22100 LUND,SWEDEN

来源：

ACTA CHEMICA SCANDINAVICA | 1990年 / 44卷 / 10期

关键词：

D O I：

10.3891/acta.chem.scand.44-1024

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The sulfur-containing 3-alkylaminochromans, 5-methoxy-3-[N-(2- methylthioethyl)-propylamino]chroman (15), 5-hydroxy-3-[N-(2-methylthioethyl)propylamino]chroman (5) and 5-methoxy-8-methylthio-3-(dipropylamino)chroman (6), have been prepared from 8-bromo-5-methoxy-3-chromanol (11). This precursor was synthesized from 3-allyloxy-4-bromoanisole (8), by a thallium(III)-mediated ring-closure reaction. Compound 11 also served as starting material for the synthesis of 8-bromo-3-(dipropylamino)-5-methoxychroman (7).

引用

页码：1024 / 1028

页数：5

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