BAYESIAN ESTIMATES OF DISEASE MAPS - HOW IMPORTANT ARE PRIORS

被引:176
作者
BERNARDINELLI, L [1 ]
CLAYTON, D [1 ]
MONTOMOLI, C [1 ]
机构
[1] INST PUBL HLTH,MRC,BIOSTAT UNIT,CAMBRIDGE CB2 2SR,ENGLAND
关键词
D O I
10.1002/sim.4780142111
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In the fully Bayesian (FB) approach to disease mapping the choice of the hyperprior distribution of the dispersion parameter is a key issue. In this context we investigated the sensitivity of the rate ratio estimates to the choice of the hyperprior via a simulation study. We also compared the performance of the FB approach to mapping disease risk to the conventional approach of mapping maximum likelihood (ML) estimates and p-values. The study was modelled on the incidence data of insulin dependent diabetes mellitus (IDDM) as observed in the communes of Sardinia.
引用
收藏
页码:2411 / 2431
页数:21
相关论文
共 20 条
[1]   EMPIRICAL BAYES VERSUS FULLY BAYESIAN-ANALYSIS OF GEOGRAPHICAL VARIATION IN DISEASE RISK [J].
BERNARDINELLI, L ;
MONTOMOLI, C .
STATISTICS IN MEDICINE, 1992, 11 (08) :983-1007
[2]  
BERNARDINELLI L, 1994, ATLAS CANCER MORTALI
[3]   BAYESIAN IMAGE-RESTORATION, WITH 2 APPLICATIONS IN SPATIAL STATISTICS [J].
BESAG, J ;
YORK, J ;
MOLLIE, A .
ANNALS OF THE INSTITUTE OF STATISTICAL MATHEMATICS, 1991, 43 (01) :1-20
[4]  
BIGGERI A, 1995, J ITALIAN STATISTICA, V2, P251
[5]  
BRESLOW NE, 1993, J AM STAT ASSOC, V88, P421
[6]  
BRESLOW NE, 1984, APPL STAT-J ROY ST C, V33, P38
[7]   EMPIRICAL BAYES ESTIMATES OF AGE-STANDARDIZED RELATIVE RISKS FOR USE IN DISEASE MAPPING [J].
CLAYTON, D ;
KALDOR, J .
BIOMETRICS, 1987, 43 (03) :671-681
[8]  
CLAYTON DG, 1993, SMALL AREA STUDIES G
[9]  
CLAYTON DG, 1994, INT J EPIDEMIOL, V22, P1193
[10]  
CLAYTON DG, 1989, 14TH P INT BIOM C, P201