SIGNIFICANCE OF COMMON ACUTE LYMPHOBLASTIC-LEUKEMIA ANTIGEN (CALLA) POSITIVE CELLS IN BONE-MARROW OF CHILDREN OFF THERAPY IN COMPLETE REMISSION

被引：13
作者：
SELF, SE
MORGAN, S
GRUSH, O
LAVIA, MF
机构：
[1] MED UNIV S CAROLINA,DEPT LAB MED,CHARLESTON,SC 29425
[2] MED UNIV S CAROLINA,DEPT PEDIAT,CHARLESTON,SC 29425
来源：
HEMATOLOGICAL ONCOLOGY | 1990年 / 8卷 / 02期
关键词：
ALL; cALLA positive cells; Hematogones; Pediatric leukemia;
D O I：
10.1002/hon.2900080204
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Bone marrows from 21 children with acute lymphoblastic leukemia in complete remission (CR) and off therapy for 14 months to 10 years were examined by flow cytometry with a panel of monoclonal antibodies. Significant percentages of cALLA + cells of low fluorescence intensity were present up to 9 years after CR. These results emphasize the need to interpret flow cytometry results in light of the findings that low intensity cALLA + cells represent a normal population of immature, non‐malignant lymphoid cells. Copyright © 1990 John Wiley & Sons, Ltd
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页码：91 / 95
页数：5
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