Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi. It is the most common reported vector-borne illness in the United States. The clinical course of Lyme disease is divided into early and late phases. Early disease may be limited or disseminated. Generally, cardiac complications occur in the early disseminated phase. Disturbance of atrioventicular conduction is the most commonly recognized cardiac manifestation of Lyme disease. This is usually self-limited and does not require permanent cardiac pacing. A case of Lyme carditis with atrioventricular block requiring permanent pacing is reported and the indications for cardiac pacing in this disease are reviewed.