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[21]
STEWART JM, 1985, SOLID PHASE PEPTIDE
ONE-DIMENSIONAL AND TWO-DIMENSIONAL H-1-NMR STUDY OF THE SUBSTANCE-P FRAGMENT ARG-PRO-LYS-PRO
被引：10
作者：
OTTER, A
KOTOVYCH, G
STEWART, JM
机构：
[1] UNIV ALBERTA, DEPT CHEM, EDMONTON T6G 2G2, ALBERTA, CANADA
[2] UNIV COLORADO, DEPT BIOCHEM, DENVER, CO 80262 USA
关键词：
D O I：
10.1080/07391102.1986.10508489
中图分类号：
Q5 [生物化学];
Q7 [分子生物学];
学科分类号：
071010 ;
081704 ;
摘要：
The Substance P fragment Arg1-Pro2-Lys3-Pro4 (SP1-4) has been extensively investigated by means of proton nuclear magnetic resonance at 400 MHz. The combined application of different 2D techniques and a comparison of SP1-4 with its derivative SP1-4-amide allowed the complete and unambiguous assignment of the proton NMR spectrum. Conformational data obtained from the different NMR parameters are compared with theoretical calculations. The results suggest that SP1-4 exists, at the chosen experimental conditions, as a stretched molecule.
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页码：1121 / 1131
页数：11
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