STEREOSPECIFIC BINDING OF CHEMICALLY-MODIFIED SALEN-TYPE SCHIFF-BASE COMPLEXES OF COPPER(II) WITH DNA [SALEN=BIS(SALICYCLIDENE)ETHYLENEDIAMINE]

被引:45
|
作者
SATO, K
CHIKIRA, M
FUJII, Y
KOMATSU, A
机构
[1] CHUO UNIV,DEPT APPL CHEM,BUNKYO KU,TOKYO 112,JAPAN
[2] IBARAKI UNIV,DEPT CHEM,MITO,IBARAKI 310,JAPAN
关键词
D O I
10.1039/c39940000625
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
DNA-fibre ESR measurements reveal that the orientation of water-soluble cationic salen-type Schiff base complexes of copper(ii) on DNA changes by modification of the bridging group between two imino nitrogens in the complex; the 1,2-phenylenediamine and 2,3-naphthalenediamine bridges enable the complex to intercalate to DNA, while the ethylenediamine bridge induces groove binding.
引用
收藏
页码:625 / 626
页数:2
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