1-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)-5-ETHYLURACIL - A HIGHLY SELECTIVE ANTIHERPES SIMPLEX AGENT

被引：36
作者：
MANSURI, MM
GHAZZOULI, I
CHEN, MS
HOWELL, HG
BRODFUEHRER, PR
BENIGNI, DA
MARTIN, JC
机构：
[1] BRISTOL MYERS CO,DIV PHARMACEUT RES & DEV,WALLINGFORD,CT 06492
[2] BRISTOL MYERS CO,DEPT VIROL,WALLINGFORD,CT 06492
[3] BRISTOL MYERS CO,DEPT CHEM PROC,WALLINGFORD,CT 06492
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 05期
关键词：
D O I：
10.1021/jm00388a021
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：867 / 871
页数：5
相关论文
共 35 条
[1]   COMPARISON OF THERAPEUTIC EFFECTS OF 5 ANTI-VIRAL AGENTS ON CUTANEOUS HERPESVIRUS INFECTION IN GUINEA-PIGS [J].
ALENIUS, S ;
OBERG, B .
ARCHIVES OF VIROLOGY, 1978, 58 (04) :277-288
[2]  
ALLAUDEEN HS, 1982, J BIOL CHEM, V257, P1879
[3]   KINETICS OF THE INTERACTION OF MONOPHOSPHATES OF THE ANTIVIRAL NUCLEOSIDES 2'-FLUORO-1-BETA-D-ARABINOFURANOSYLPYRIMIDINE AND (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE WITH THYMIDYLATE KINASES FROM VERO CELLS AND HERPES-SIMPLEX VIRUS TYPE-1 AND TYPE-2 [J].
CHEN, MS ;
AMICO, LA ;
SPEELMAN, DJ .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1984, 26 (05) :778-780
[4]  
CHEN MS, 1978, J BIOL CHEM, V253, P1325
[5]  
CHEN MS, 1976, J BIOL CHEM, V251, P6555
[6]   DIFFERENTIAL ACTIVITY OF POTENTIAL ANTI-VIRAL NUCLEOSIDE ANALOGS ON HERPES-SIMPLEX VIRUS-INDUCED AND HUMAN CELLULAR THYMIDINE KINASES [J].
CHENG, YC ;
DUTSCHMAN, G ;
FOX, JJ ;
WATANABE, KA ;
MACHIDA, H .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1981, 20 (03) :420-423
[7]  
CHENG YC, 1976, J BIOL CHEM, V251, P2605
[8]  
CHOU TC, 1981, CANCER RES, V41, P3336
[9]  
CHOU TC, 1985, P AM ASSOC CANC RES, V26, P333
[10]  
CODERRE JA, 1983, J MED CHEM, V26, P1149
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