A CLUSTER OF DISPENSABLE GENES WITHIN THE HUMAN CYTOMEGALOVIRUS GENOME SHORT COMPONENT - IRS1, US1 THROUGH US5, AND THE US6 FAMILY

被引:83
作者
JONES, TR
MUZITHRAS, VP
机构
关键词
D O I
10.1128/JVI.66.4.2541-2546.1992
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
By insertional mutagenesis, human cytomegalovirus recombinants deleted of each of the US6 glycoprotein family genes were isolated. A recombinant lacking IRS1, US1 through US5, and most of the US6 family was also isolated. The growth kinetics of these mutants were similar to that of the wild type. A dispensable cluster of genes was identified.
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页码:2541 / 2546
页数:6
相关论文
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