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INTERACTIONS OF HTF4 WITH E-BOX MOTIFS IN THE LONG TERMINAL REPEAT OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1
被引:20
|作者:
YI, Z
[1
]
DOYLE, K
[1
]
BINA, M
[1
]
机构:
[1] PURDUE UNIV, DEPT CHEM, W LAFAYETTE, IN 47907 USA
关键词:
D O I:
10.1128/JVI.66.9.5631-5634.1992
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
We have identified three consensus E-box motifs in the long terminal repeat of human immunodeficiency virus type 1. One of these E boxes interacts selectively with representative members of the class A group of basic helix-loop-helix proteins, including HTF4, E47, and their heterodimers. Our analyses implicate the helix-loop-helix proteins in regulation of human immunodeficiency virus type 1 gene expression.
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页码:5631 / 5634
页数:4
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