ASSESSMENT OF CYTOTOXIC AND GENOTOXIC POTENTIALS OF OCCUPATIONALLY PESTICIDE EXPOSED POPULATION

被引：0
|
作者：
Didla, Swarupa Rani [1 ]
Sairam, P. V. V. Gowri [1 ]
Chitti, Sashikanth [1 ]
机构：
[1] Mol Sci Pvt Ltd, Translat Res Inst, TRIMS LABS, 2-35-72 Sai Narsimha Towers,Sect 10, Visakhapatnam 530017, Andhra Pradesh, India
来源：
INTERNATIONAL JOURNAL OF ADVANCED BIOTECHNOLOGY AND RESEARCH | 2011年 / 2卷 / 03期
关键词：
Sister Chromatid Exchanges; Genotoxicity; Cytotoxicity; DNA Damage; Pesticide exposed population;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Biomonitoring markers are gaining considerable importance in epidemiological and experimental biology studies to achieve both a measurement and an estimation of biologically active/passive exposure to genotoxic pollutants. A wide range of chemical products known to be acutely toxic is currently used in the agricultural sector, including numerous pesticides with different compositions. People working in the chemical industry producing pesticides, people spraying pesticides and people dedicated to floriculture or agricultural works in general are the subject of specific sections. In the present study we analysed the cytotoxic and genotoxic effects of pesticides in workers exposed to pesticides by comparing to normal population. The mean mitotic index was higher in pesticide exposed population with 2.029 compared to 5.1 of control samples. SCE's and Cell proliferation kinetics of pesticide exposed population were also statistically significant with mean of 21.194 and 0.321 compared to mean of control samples 5.243 and.04371 respectively.
引用
收藏
页码：395 / 399
页数：5
相关论文
共 50 条
  • [21] URINARY-EXCRETION OF PENTACHLOROPHENOL IN AN OCCUPATIONALLY EXPOSED POPULATION
    COMSTOCK, EG
    CLINICAL TOXICOLOGY, 1974, 7 (02): : 208 - 208
  • [22] Cytogenetic monitoring in a population occupationally exposed to pesticides in Ecuador
    Paz-y-Miño, C
    Bustamante, G
    Sánchez, ME
    Leone, PE
    ENVIRONMENTAL HEALTH PERSPECTIVES, 2002, 110 (11) : 1077 - 1080
  • [23] The frequency of induced premature centromere division in human populations occupationally exposed to genotoxic chemicals
    Major, J
    Jakab, MG
    Tompa, A
    MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 1999, 445 (02) : 241 - 249
  • [24] Genotoxic evaluation of welders occupationally exposed to chromium and nickel using the Comet and micronucleus assays
    Danadevi, K
    Rozati, R
    Banu, BS
    Grover, P
    MUTAGENESIS, 2004, 19 (01) : 35 - 41
  • [25] Unraveling chromosomal and genotoxic damage in individuals occupationally exposed to coal from underground mining
    Buitrago-Rodriguez, Maria Yolanda
    Rangel, Nelson
    Vega-Valderrama, Juan D.
    Pulido-Medellin, Martin
    Rondon-Lagos, Milena
    FRONTIERS IN GENETICS, 2024, 15
  • [26] Cytogenetic analysis of Pakistani individuals occupationally exposed to pesticides in a pesticide production industry
    Bhalli, JA
    Khan, QM
    Haq, MA
    Khalid, AM
    Nasim, A
    MUTAGENESIS, 2006, 21 (02) : 143 - 148
  • [27] In Vitro Cytotoxic, Genotoxic, Embryotoxic and Oxidative Damage Potentials by Empagliflozin
    Cadirci, Kenan
    Turkez, Hasan
    Tozlu, Ozlem Ozdemir
    Yapca, Omer Erkan
    Bayrak, Muharrem
    Emsen, Bugrahan
    Mardinoglu, Adil
    BIOLOGY BULLETIN, 2024, 51 (02) : 243 - 250
  • [28] Cytotoxic and genotoxic potentials of newly synthesized antiviral aminopyrazoloquinoline derivatives
    Jamal M. Arif
    Mohammed Kunhi
    Manogaran P. Subramanian
    Adnan A. Bekhit
    Ola A. El-Sayed
    Khalid Al-Hussein
    Hassan Y. Aboul-Enein
    Fahad M. Al-Khodairy
    Medicinal Chemistry Research, 2008, 17 : 297 - 304
  • [29] Cytotoxic and genotoxic potentials of newly synthesized antiviral aminopyrazoloquinoline derivatives
    Arif, Jamal M.
    Kunhi, Mohammed
    Subramanian, Manogaran P.
    Bekhit, Adnan A.
    El-Sayed, Ola A.
    Al-Hussein, Khalid
    Aboul-Enein, Hassan Y.
    Al-Khodairy, Fahad M.
    MEDICINAL CHEMISTRY RESEARCH, 2008, 17 (2-7) : 297 - 304
  • [30] Assessment of cytotoxic and genotoxic potentials of a mononuclear Fe(II) Schiff base complex with photocatalytic activity in Trigonella
    Mahapatra, Kalyan
    Ghosh, Ayon Kanti
    De, Sayanti
    Ghosh, Noyel
    Sadhukhan, Pritam
    Chatterjee, Sharmistha
    Ghosh, Rajarshi
    Sil, Parames C.
    Roy, Sujit
    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 1864 (03):
12345