A NOVEL ALTERNATIVE SPLICE DOMAIN IN ZEBRAFISH TENASCIN-C

被引：5

作者：

QIAO, T ^{[1
]}

MADDOX, BK ^{[1
]}

ERICKSON, HP ^{[1
]}

机构：

[1] DUKE UNIV,MED CTR,DEPT CELL BIOL,DURHAM,NC 27710

来源：

GENE | 1995年 / 156卷 / 02期

关键词：

FIBRONECTIN; FIBRINOGEN; EXTRACELLULAR MATRIX;

D O I：

10.1016/0378-1119(95)00039-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We have identified and sequenced clones from a zebrafish library that correspond to tenascin-C (TN-C). The 2036-bp sequence covers the C-terminal segment of the protein. Comparison of this sequence to TN-C from other vertebrates indicates that our sequence starts in FN-III domain 5, continues with one alternative splice domain, then with FN-III domains 6-8 and, finally, the complete fibrinogen-like domain. The alternative splice domain, designated TNfnQ, is not closely identified to any of the domains in other species, and may represent a novel descendent of the alternative splice-domain precursor.

引用

页码：307 / 308

页数：2