STUDIES ON REACTIONS OF NUCLEOSIDE H-PHOSPHONATES WITH BIFUNCTIONAL REAGENTS .3. FURTHER-STUDIES ON TRANSESTERIFICATION OF NUCLEOSIDE H-PHOSPHONATE DIESTERS WITH AMINO-ALCOHOLS

被引：5
|
作者：
SOBKOWSKI, M
STAWINSKI, J
SOBKOWSKA, A
KRASZEWSKI, A
机构：
[1] POLISH ACAD SCI,INST BIOORGAN CHEM,PL-60704 POZNAN,POLAND
[2] UNIV STOCKHOLM,ARRHENIUS LAB,DEPT ORGAN CHEM,S-10691 STOCKHOLM,SWEDEN
来源：
NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期
基金：
瑞典研究理事会;
关键词：
D O I：
10.1080/15257779508012484
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Reactions of 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl 2-cyanoethyl phosphonate with alcohols, amines and amino alcohols in pyridine are described. Transesterification was found to be faster than beta-elimination of 2-cyanoethyl group.
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页码：839 / 842
页数：4
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