Tumor Lysis Syndrome in Childhood

被引：0

作者：

Yuksel, Selcuk ^{[1
]}

Ekim, Mesiha ^{[1
]}

Yalcinkaya, Fatos ^{[1
]}

机构：

[1] Ankara Univ, Tip Fak, TR-06100 Ankara, Turkey

来源：

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL | 2005年 / 14卷 / 02期

关键词：

tumor lysis syndrome; childhood;

D O I：

暂无

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Tumor lysis syndrome (TLS) is a clinical condition that results from rapid destruction of the tumor cells and it is associated with life-threatening metabolic abnormalities. These metabolic abnormalities are hyperuricemia, hyperkalemia, hyperphosphatemia and secondary development of hypocalcemia. TLS is seen most frequently in patients with lymphoproliferative malignancies. The most important point of treatment is early identification of patients that are at risk for the development of TLS and its prevention. Nephrology clinics are closely interested in TLS because generally the metabolic abnormalities occur together with the acute renal failure. This review focuses on basic background information, pathogenesis and preventive as well as therapeutic strategies concerning TLS.

引用

页码：57 / 61

页数：5

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