KINETIC BASIS FOR INSENSITIVITY TO TETRODOTOXIN AND SAXITOXIN IN SODIUM-CHANNELS OF CANINE HEART AND DENERVATED RAT SKELETAL-MUSCLE

被引:88
作者
GUO, XT
UEHARA, A
RAVINDRAN, A
BRYANT, SH
HALL, S
MOCZYDLOWSKI, E
机构
[1] YALE UNIV, SCH MED, DEPT PHARMACOL, NEW HAVEN, CT 06510 USA
[2] UNIV CINCINNATI, COLL MED, DEPT PHARMACOL & CELL BIOPHYS, CINCINNATI, OH 45267 USA
[3] FUKUOKA UNIV, SCH MED, DEPT PHYSIOL, FUKUOKA 81401, JAPAN
[4] US FDA, WASHINGTON, DC 20204 USA
关键词
D O I
10.1021/bi00398a003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:7546 / 7556
页数:11
相关论文
共 76 条
[1]   VOLTAGE-DEPENDENT ACTION OF TETRODOTOXIN IN MAMMALIAN CARDIAC-MUSCLE [J].
BAER, M ;
BEST, PM ;
REUTER, H .
NATURE, 1976, 263 (5575) :344-345
[2]   CHARACTERISTICS OF SAXITOXIN BINDING TO THE SODIUM-CHANNEL OF SARCOLEMMA ISOLATED FROM RAT SKELETAL-MUSCLE [J].
BARCHI, RL ;
WEIGELE, JB .
JOURNAL OF PHYSIOLOGY-LONDON, 1979, 295 (OCT) :383-396
[3]   BIOCHEMISTRY OF SODIUM-CHANNELS FROM MAMMALIAN MUSCLE [J].
BARCHI, RL .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1986, 479 :179-185
[4]   EVALUATION OF INTRINSIC BINDING-ENERGY FROM A HYDROGEN-BONDING GROUP IN AN ENZYME-INHIBITOR [J].
BARTLETT, PA ;
MARLOWE, CK .
SCIENCE, 1987, 235 (4788) :569-571
[5]  
BROWN AM, 1981, J PHYSIOL-LONDON, V318, P479
[6]   KINETIC AND PHARMACOLOGICAL PROPERTIES OF SODIUM CHANNEL OF FROG SKELETAL-MUSCLE [J].
CAMPBELL, DT ;
HILLE, B .
JOURNAL OF GENERAL PHYSIOLOGY, 1976, 67 (03) :309-323
[7]   THE MOLECULAR-BASIS OF NEURONAL EXCITABILITY [J].
CATTERALL, WA .
SCIENCE, 1984, 223 (4637) :653-661
[8]  
CATTERALL WA, 1981, MOL PHARMACOL, V20, P526
[9]   TETRODOTOXIN BLOCK OF SODIUM-CHANNELS IN RABBIT PURKINJE-FIBERS - INTERACTIONS BETWEEN TOXIN BINDING AND CHANNEL GATING [J].
COHEN, CJ ;
BEAN, BP ;
COLATSKY, TJ ;
TSIEN, RW .
JOURNAL OF GENERAL PHYSIOLOGY, 1981, 78 (04) :383-411
[10]  
Colquhoun D., 1983, SINGLE CHANNEL RECOR, P135