MELATONIN: A NOVEL BIOMATERIAL FOR IMMUNOTHERAPY

被引：2

作者：

Aher, Vaibhav D. ^{[1
]}

Wahi, Arun Kumar ^{[2
]}

机构：

[1] NIMS Univ, Inst Pharm, Jaipur, Rajasthan, India

[2] MIT, Coll Pharm, Moradabad, Uttar Pradesh, India

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | 2011年 / 2卷 / 04期

关键词：

Melatonin; Immunity; Antioxidant; Pineal gland;

D O I：

10.13040/IJPSR.0975-8232.2(4).772-77

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The mainly deliberate endocrine product of the pineal gland, melatonin, has been reported to be involved in the feedback between neuroendocrine and immune functions and to exert oncostatic action, at least in certain experimental conditions. Melatonin seems to be a vital part of the immune system, by exerting direct and/or indirect stimulatory effects on both cellular and humoral immunity. Likewise, an antitumor activity of melatonin has been shown in several experimental models in vivo and in vitro. The means by which melatonin exerts its effects on immunity and neoplastic growth have not been elucidated. The different putative mechanisms of action of melatonin investigated so far are at this juncture briefly discussed.

引用

页码：772 / 777

页数：6

共 31 条

[1] Melatonin: therapeutic and clinical utilization [J].