TOTAL SYNTHESIS OF THE ANTIFUNGAL AGENT PAPULACANDIN-D

被引：25

作者：

BARRETT, AGM ^{[1
]}

PENA, M ^{[1
]}

WILLARDSEN, JA ^{[1
]}

机构：

[1] COLORADO STATE UNIV,DEPT CHEM,FT COLLINS,CO 80523

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 11期

关键词：

D O I：

10.1039/c39950001147

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Condensation of 2,3,4,6-tetra-O-(trimethylsilyl)-D-gluconolactone with tert-butyl[2-lithio-3,5-di-(triisopropylsilyloxy)benzyloxy]dimethylsilane, protection of the resultant spiroketal with di(tert-butyl)silyl di(trifluoromethanesulfonate), selective O-3'-esterification and deprotection gives papulacandin D.

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页码：1147 / 1148

页数：2

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