CANDIDA ALBICANS;
CANDIDIASIS;
EPIDEMIOLOGY;
ANTIFUNGAL DRUG RESISTANCE;
AIDS;
D O I:
10.1016/0195-6701(95)90036-5
中图分类号:
R1 [预防医学、卫生学];
学科分类号:
1004 ;
120402 ;
摘要:
The increase in infections due to Candida over the past decade is significant. This is particularly true for hospitalized patients where the rate of blood-stream infection due to Candida spp. has increased by almost 500% over the decade of the 1980s. This increase is accompanied by a significant excess mortality and a prolonged length of stay in the hospital. This trend continues into the 1990s where in the US Candida spp. remains the fourth most common blood-stream pathogen, accounting for 8% of all hospital-acquired blood-stream infections. Notably, more than one-third of candidal blood-stream infections are caused by species other than C. albicans. The majority of these infections arise from an endogenous focus of colonization; however, the documentation of nosocomial transmission or 'cross-infection' and the recognition of resistance to antifungal agents pose new and significant problems. Recent studies indicate that Candida may be isolated from the hands of 15-54% of health care workers in the intensive care unit setting and that the strain of Candida carried on the hands may be shared by infected patients. These studies are facilitated by molecular typing and careful epidemiological investigation and suggest that cross-infection is an important and preventable feature of candidal blood-stream infection. Both endogenous and exogenous sources of infection are now well-documented and such information should help direct measures to prevent infections in high risk individuals.
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
BANERJEE, SN
EMORI, TG
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
EMORI, TG
CULVER, DH
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
CULVER, DH
GAYNES, RP
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
GAYNES, RP
JARVIS, WR
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
JARVIS, WR
HORAN, T
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
HORAN, T
EDWARDS, JR
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
EDWARDS, JR
TOLSON, J
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
TOLSON, J
HENDERSON, T
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
HENDERSON, T
MARTONE, WJ
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
机构:
UNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCEUNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCE
BARTDELABESSE, E
BOIRON, P
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCEUNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCE
BOIRON, P
CARLOTTI, A
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCEUNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCE
CARLOTTI, A
DUPONT, B
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCEUNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCE
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
BANERJEE, SN
EMORI, TG
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
EMORI, TG
CULVER, DH
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
CULVER, DH
GAYNES, RP
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
GAYNES, RP
JARVIS, WR
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
JARVIS, WR
HORAN, T
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
HORAN, T
EDWARDS, JR
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
EDWARDS, JR
TOLSON, J
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
TOLSON, J
HENDERSON, T
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
HENDERSON, T
MARTONE, WJ
论文数: 0引用数: 0
h-index: 0
机构:Hospital Infections Program, Center for Infectious Diseases, Centers for Disease Control, United States Public Health Service, Department of Health and Human Services, Atlanta
机构:
UNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCEUNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCE
BARTDELABESSE, E
BOIRON, P
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCEUNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCE
BOIRON, P
CARLOTTI, A
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCEUNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCE
CARLOTTI, A
DUPONT, B
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCEUNIV CLAUDE BERNARD LYON 1, MYCOL FONDAMENTALE & APPL BIOTECHNOL IND LAB, F-69373 LYON, FRANCE