ISOLATION OF PEPSINOGEN A FROM GASTRIC-MUCOSA OF BULLFROG, RANA-CATESBEIANA

被引：12
|
作者：
INOKUCHI, T
KOBAYASHI, K
HORIUCHI, S
机构：
[1] Life Science Institute, Sophia University, Chiyoda-ku, Tokyo, 102
来源：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1995年 / 111卷 / 01期
关键词：
ACID PROTEINASE; ANURAN; BULLFROG; NH2-TERMINAL SEQUENCE; PEPSINOGEN A; PROGASTRICSIN; RANA CATESBEIANA; STOMACH;
D O I：
10.1016/0305-0491(94)00219-K
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two pepsinogens, named pepsinogens II-2 and III, were purified from the gastric mucosa of the bullfrog, Rana catesbeiana, The two pepsinogens were distinct from each other with respect to activation rate, sensitivity to pepstatin, amino acid composition, immunogenicity and NH2-terminal sequence. The analysis of NH2-terminal sequence showed that pepsinogen II-2 is identical to progastricsin from the bullfrog esophagus, Pepsinogen III was thought to be pepsinogen III which has so far not been found in the bullfrog.
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页码：111 / 117
页数：7
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