T-CELL BASED CANCER-IMMUNOTHERAPY - DIRECT OR REDIRECTED TUMOR-CELL RECOGNITION

被引：52
作者：
BEUN, GDM
VANDEVELDE, CJH
FLEUREN, GJ
机构：
[1] ACAD HOSP LEIDEN, DEPT PATHOL, 2300 RC LEIDEN, NETHERLANDS
[2] DR DANIEL DEN HOED CANC CTR, 3008 AE ROTTERDAM, NETHERLANDS
来源：
IMMUNOLOGY TODAY | 1994年 / 15卷 / 01期
关键词：
D O I：
10.1016/0167-5699(94)90019-1
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In development of strategies for immunotherapy of cancer a new emphasis is emerging, termed T-cell retargeting, which involves artificial redirection of cytotoxic T lymphocytes (CTL) against cancer cells, using bispecific reagents. In this article, Gideon Beun, Cornelis van de Velde and Gert Jan Fleuren evaluate this potential strategy for cellular immunotherapy, and propose how the gap between in vitro results and clinical application might be bridged.
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页码：11 / 15
页数：5
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