CALCIUM SIGNALS IN OLFACTORY NEURONS

被引：53

作者：

TAREILUS, E ^{[1
]}

NOE, J ^{[1
]}

BREER, H ^{[1
]}

机构：

[1] UNIV STUTTGART HOHENHEIM,INST ZOOPHYSIOL,D-70593 STUTTGART,GERMANY

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | 1995年 / 1269卷 / 02期

关键词：

CALCIUM; OLFACTORY NEURON; FLUORESCENCE;

D O I：

10.1016/0167-4889(95)00105-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Laser scanning confocal microscopy in combination with the fluorescent calcium indicators Fluo-3 and Fura-Red was employed to estimate the intracellular concentration of free calcium ions in individual olfactory receptor neurons and to monitor temporal and spatial changes in the Ca2+-level upon stimulation. The chemosensory cells responded to odorants with a significant increase in the calcium concentration, preferentially in the dendritic knob. Applying various stimulation paradigma, it was found that in a population of isolated cells, subsets of receptor neurons display distinct patterns of responsiveness.

引用

页码：129 / 138

页数：10

共 43 条

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