OPTICAL PURITY DETERMINATION OF THYROXINE ENANTIOMERS IN BULK MATERIALS BY CHIRAL THIN-LAYER CHROMATOGRAPHY

被引：9

作者：

ABOULENEIN, HY

SERIGNESE, V

机构：

[1] Bioanalytical and Drug development Laboratory, Biological and Medical Research Department (MBC-03), King Faisal Specialist Hospital and Research Centre, Riyadh, 11211

来源：

BIOMEDICAL CHROMATOGRAPHY | 1994年 / 8卷 / 06期

关键词：

D O I：

10.1002/bmc.1130080616

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

L-thyroxine and D-thyroxine were separated on ligand exchange chiral thin layer chromatographic plates, using a solvent system consisting of acetonitrile:methanol:water 60:15:15 v/v, at a wavelength of 254 nm. The methodology, chiral recognition mechanism(s) involved and its application are discussed.

引用

页码：317 / 318

页数：2

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