CLONING AND SEQUENCING OF A C-MYC GENE FROM GOLDFISH CARASSIUS-AURATUS

被引：2

作者：

ZHANG, H ^{[1
]}

OKAMOTO, N ^{[1
]}

IKEDA, Y ^{[1
]}

机构：

[1] TOKYO UNIV FISHERIES,DEPT AQUAT BIOSCI,MINATO KU,TOKYO 108,JAPAN

来源：

FISHERIES SCIENCE | 1994年 / 60卷 / 06期

关键词：

GOLDFISH; TETRAPLOIDY; C-MYC GENE; CLONING; NUCLEOTIDE SEQUENCE; GENOMIC ORGANIZATION;

D O I：

10.2331/fishsci.60.707

中图分类号：

S9 [水产、渔业];

学科分类号：

0908 ;

摘要：

A proto-oncogene, cellular myc (c-myc) gene, has been isolated from a tetraploid fish, goldfish Carassius auratus. The nucleotide sequence of 5021 base pairs covering the gene and its flanking regions was determined. The goldfish c-myc gene, probably like those of other animals, consists of two coding exons (exon 2 and exon 3) interrupted by an intron. Exon 2 and 3 together presumably encode a protein of 399 amino acid (aa) residues. The goldfish c-myc gene shares higher aa identities with those of the common carp (93.0% and 95.3%) and zebra fish (90.7%) than with those of rainbow trout (71.9%) or humans (56.0%).

引用

页码：707 / 711

页数：5

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