TANDEM ENYNE ALLENE-RADICAL CYCLIZATION VIA [3,3]-SIGMATROPIC REARRANGEMENTS

被引：30
|
作者：
GRISSOM, JW
HUANG, DH
机构：
[1] Department of Chemistry, University of Utah, Salt Lake City
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 18期
关键词：
D O I：
10.1021/jo00097a002
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Enediynes 1, 7, 12, and 16 undergo a tandem [3,3] sigmatropic shift-enyne allene cyclization. Enediynes 7 and 16 are especially interesting because after undergoing a [3,3] sigmatropic shift and enyne allene cyclization, the resultant biradical undergoes a 5-exo radical cyclization. These reactions can be effected by either heating at 150 degrees C or by treatment with silver salts followed by heating at 75 degrees C.
引用
收藏
页码：5114 / 5116
页数：3
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