Aggressive Angiomyxoma with Diffusion-Weighted Magnetic Resonance Imaging and Dynamic Contrast Enhancement: A Case Report and Review of the Literature

Introduction: Aggressive angiomyxoma (AA) is a rare benign soft tissue tumour usually affecting the pelvis and perineum of young women. Magnetic resonance imaging (MRI) is crucial in the management of AA patients for its diagnostic contribution and for the preoperative assessment of the actual tumour extension. Given the current development of less aggressive therapeutics associated with a higher risk of recurrence, close follow-up with MRI is fundamental after treatment. In this context, diffusion-weighted (DW) imaging has already shown high efficacy in the detection of early small relapses in prostate or rectal cancer. Case Report: We report here a case of pelvic AA in a 51-year-old woman examined with dynamic contrast enhancement and DW-MRI, including apparent diffusion coefficient mapping and calculation. Conclusion: To our knowledge, this is the first description of DWMRI in AA reported in the literature. Here, knowledge about imaging features of AA will be reviewed and expanded. (C) 2013 S. Karger AG, Basel