Concomitant presentation of myocarditis and non-bacterial thrombotic endocarditis in a patient with granulomatosis with polyangiitis

被引:1
作者
Yazdi, Amirhossein [1 ]
Olfat, Mehrnaz [1 ]
Beni, Hassan Riahi [2 ]
Bikdeli, Behnood [3 ,4 ]
机构
[1] Hamedan Univ Med Sci, Sch Med, Dept Cardiol, Hamadan, Iran
[2] Univ Med Sci, Sch Med, Dept Cardiol, Tehran, Iran
[3] Yale New Haven Med Ctr, Ctr Outcomes Res & Evaluat, New Haven, CT USA
[4] Yale New Haven Med Ctr, Dept Internal Med, New Haven, CT USA
关键词
granulomatosis with polyangiitis; myocarditis; nonbacterial thrombotic endocarditis; antineutrophil cytoplasmic antibody;
D O I
10.4081/rr.2014.5078
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Granulomatosis with polyangiitis (GPA) is a necrotizing vasculitis. The etiology of the disease is not completely known. In this report, we describe a 47-year-old male who presented with ongoing dyspnea. He is a known case of GPA for 3 years based on skin biopsy and positive antineutrophil cytoplasmic antibody. The electrocardiogram showed changes suggestive for myocarditis. A transthoracic and trans esophageal echocardiogram revealed left ventricular systolic dysfunction, thickened left atrial and ventricular wall and vegetation on mitral valve. Blood cultures were negative. Myocarditis and nonbacterial thrombotic endocarditis (NBTE) were diagnosed. As far as we know, NBTE is a rare manifestation of GPA and its presentation with myocarditis is not reported to date. This case indicates the uncommon manifestations of GPA and notifies the importance of performing echocardiography in order to prevent life threatening cardiac complications of the disease.
引用
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页码:1 / 3
页数:3
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