Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis

被引:15
作者
Ishida, Ko [1 ]
Aota, Yoichi [2 ]
Mitsugi, Naoto [1 ]
Kono, Motonori [2 ]
Higashi, Takayuki [3 ]
Kawai, Takuya [2 ]
Yamada, Katsutaka [3 ]
Niimura, Takanori [2 ]
Kaneko, Kanichiro [3 ]
Tanabe, Hironori [3 ]
Ito, Yohei [1 ]
Katsuhata, Tomoyuki [1 ]
Saito, Tomoyuki [3 ]
机构
[1] Yokohama City Univ Med Ctr, Dept Orthopaed Surg, Minami Ku, 4-57 Urafune, Yokohama, Kanagawa 2320024, Japan
[2] Yokohama City Brain & Stroke Ctr, Dept Orthopaed Surg, Isogo Ku, Yokohama, Kanagawa 2350012, Japan
[3] Yokohama City Univ, Dept Orthopaed Surg, Kanazawa Ku, Yokohama, Kanagawa 2360004, Japan
来源
SCOLIOSIS AND SPINAL DISORDERS | 2015年 / 10卷
关键词
D O I
10.1186/s13013-015-0033-z
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Several authors have confirmed that 27 to 38% of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59% of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients.
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页数:5
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