A FACILE PREPARATION OF 2-SUBSTITUTED AND 5-SUBSTITUTED 3-BROMOTHIOPHENES

被引：21

作者：

MASQUELIN, T ^{[1
]}

OBRECHT, D ^{[1
]}

机构：

[1] F HOFFMANN LA ROCHE & CIE AG,PHARMA RES,CH-4002 BASEL,SWITZERLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 50期

关键词：

D O I：

10.1016/S0040-4039(00)78549-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acetylenic ketones of type 4 and acetylenic acetals of type 6 (Scheme 1) are excellent cyclization precursors for the acid-catalyzed synthesis of various heterocycles. Using this methodology, 5- and 2-substituted 3-bromothiophenes of types 7 and 8 have been prepared in good to excellent yields.

引用

页码：9387 / 9390

页数：4

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