HYPERTENSION IN AUTOSOMAL-DOMINANT POLYCYSTIC KIDNEY-DISEASE (ADPKD)

被引：0

作者：

ZEIER, M ^{[1
]}

MANDELBAUM, A ^{[1
]}

机构：

[1] UNIV HEIDELBERG,MED KLIN,SEKT NEPHROL,W-6900 HEIDELBERG,GERMANY

来源：

NIEREN-UND HOCHDRUCKKRANKHEITEN | 1993年 / 22卷 / 09期

关键词：

AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE; HYPERTENSION; RENIN; PROGRESSION;

D O I：

暂无

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Hypertension is a frequent complication of autosomal dominant polycystic kidney disease. More than 80% of all patients suffer from this complication. The underlying mechanisms include inappropriate renin secretion and sodium retention. Converting enzyme blockade lowers systemic blood pressure efficiently and this is paralleled by a decrease in renal vascular resistance. ACE inhibitors in autosomal dominant polycystic kidney disease may not only lower systemic blood pressure but also retard the progression of renal failure In this disease.

引用

页码：455 / 458

页数：4