OXIDATIVE-DEGRADATION OF L-ASCORBIC-ACID ACETALS TO 2',3'-DIDEOXY-3'-OXARIBOFURANOSIDES - SYNTHESIS OF ENANTIOMERICALLY PURE 2',3'-DIDEOXY-3'-OXACYTIDINE STEREOISOMERS AS POTENTIAL ANTIVIRAL AGENTS

被引：36

作者：

BELLEAU, BR ^{[1
]}

EVANS, CA ^{[1
]}

TSE, HLA ^{[1
]}

JIN, HL ^{[1
]}

DIXIT, DM ^{[1
]}

MANSOUR, TS ^{[1
]}

机构：

[1] BIOCHEM PHARMA INC,531 BLVD PRAIRIES,LAVAL H7V 1B7,QUEBEC,CANADA

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(00)60903-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantiomerically pure 2',3'-dideoxy-3'-oxacytidine nucleoside analogues were synthesized from L-ascorbic acid in eight steps and good overall yield.

引用

页码：6949 / 6952

页数：4

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