HYDROGEN-FLUORIDE MEDIATED ALKYLATION AND DIMERIZATION OF THE BASE MOIETY OF THE CIS DIASTEREOISOMERS OF 5,6-DIHYDROXY-5,6-DIHYDROTHYMIDINE

被引：0

作者：

POLVERELLI, M

BERGER, M

CADET, J

机构：

[1] Laboratoires de Chimie, Département de Recherche Fondamentale, Centre d’Etudes Nucléaires de Grenoble

来源：

NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 1-3期

关键词：

D O I：

10.1080/07328319108046527

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hydrolysis of the cis diastereoisomers of 5,6-dihydroxy-5,6-dihydrothymidine by hydrogen fluoride stabilized in pyridine in the presence of ethanol gives rise to the cis thymine glycol and the cis 6-ethoxy-5-hydroxy-5,6-dihydrothymine enantiomers.

引用

页码：563 / 564

页数：2

共 7 条

[1] Formation of 5-hydroxy-5,6-dihydrothymidine and cis-5,6-dihydroxy-5,6-dihydrothymidine in the radiolysis of N2O-Saturated aqueous solutions of thymidine, thymidine 5′-monophosphate, and DNA
Grachev, SA
Kropachev, EV
Litvyakova, GI
Chakchir, BA
HIGH ENERGY CHEMISTRY, 2001, 35 (03) : 166 - 172
[2] Formation of 5-Hydroxy-5,6-Dihydrothymidine and cis-5,6-Dihydroxy-5,6-Dihydrothymidine in the Radiolysis of N2O-Saturated Aqueous Solutions of Thymidine, Thymidine 5"-Monophosphate, and DNA
S. A. Grachev
E. V. Kropachev
G. I. Litvyakova
B. A. Chakchir
High Energy Chemistry, 2001, 35 : 166 - 172
[3] Conformational and electronic properties of the two cis (5S,6R) and (5R,6S) diastereoisomers of 5,6-dihydroxy-5,6-dihydrothymidine: X-ray and theoretical studies
Jolibois, F
Voituriez, L
Grand, A
Cadet, J
CHEMICAL RESEARCH IN TOXICOLOGY, 1996, 9 (01) : 298 - 305
[4] Synthesis and kinetic study of the deamination of the cis diastereomers of 5,6-dihydroxy-5,6-dihydro-5-methyl-2'-deoxycytidine
Bienvenu, C
Cadet, J
JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (08) : 2632 - 2637
[5] Synthesis and Kinetic Study of the Deamination of the Cis Diastereomers of 5,6-Dihydroxy-5,6-dihydro-5-methyl-2'$MI N@ deoxycytidine
Bienvenu, C.
Cadet, J.
Journal of Organic Chemistry, 61 (08):
[6] Photo-sensitized formation of the cis-(5R, 6R) diastereomer of 5,6-dihydroxy-5,6-dihydro-5-methyl-2'-deoxycytidine
Bienvenu, C
Lebrun, C
Cadet, J
JOURNAL DE CHIMIE PHYSIQUE ET DE PHYSICO-CHIMIE BIOLOGIQUE, 1997, 94 (02) : 300 - 305
[7] Detection of exposure to sprout-inhibiting radiation doses in onions via 5,6-dihydrothymidine quantification using ultrasonication-mediated DNA extraction
Fujiwara, Takuya
Fukui, Naoki
Furuta, Masakazu
Takatori, Satoshi
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 2025, 334 (01) : 595 - 602

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