SERUM CONCENTRATIONS OF 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN AND TEST-RESULTS FROM SELECTED RESIDENTS OF SEVESO, ITALY

被引：100
作者：
MOCARELLI, P
NEEDHAM, LL
MAROCCHI, A
PATTERSON, DG
BRAMBILLA, P
GERTHOUX, PM
MEAZZA, L
CARRERI, V
机构：
[1] UNIV MILAN,INST GEN PATHOL,I-20122 MILAN,ITALY
[2] CTR DIS CONTROL,CTR ENVIRONM HLTH & INJURY CONTROL,DIV ENVIRONM HLTH LAB SCI,ATLANTA,GA 30333
[3] HLTH MINIST REG LOMBARDIA,PUBL HYG SERV,MILAN,ITALY
来源：
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH | 1991年 / 32卷 / 04期
关键词：
D O I：
10.1080/15287399109531490
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
2,3,7,8-Tetrachlorodibenzo-p-dioxin levels (TCDD) were measured in serum specimens from Seveso, Italy, residents, who were potentially highly exposed to the 1976 explosion, and in controls. The residents were chosen so as to represent those who did and did not develop chloracne. Levels of TCDD as high as 56,000 parts per trillion (ppt) were found in these serum specimens that were collected in 1976. These TCDD levels are the highest ever reported, and yet almost all clinical laboratory tests on these individuals were normal; any abnormal test result was only transitory in nature. These findings are unique in linking clinical histories to TCDD levels following an acute exposure.
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页码：357 / 366
页数：10
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