MOTOR-NEURON DISEASE AND EXPOSURE TO CHEMICALS - ETIOLOGIC SUGGESTIONS FROM A CASE-CONTROL STUDY

被引：6
|
作者：
GUNNARSSON, LG
机构：
[1] Department of Neurology, Örebro Medical Center Hospital
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 1994年 / 124卷
关键词：
EPIDEMIOLOGY; AMYOTROPHIC LATERAL SCLEROSIS; ENVIRONMENT; HEREDITY; SOLVENTS;
D O I：
10.1016/0022-510X(94)90180-5
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A recent case-control study indicates that some males are genetically predisposed to develop motor neuron disease if they are exposed to chemicals, particularly solvents. Markets for such a predisposition are hereditary for a neurodegenerative disease and/or a thyroid disease. The reason for this susceptibility might be pharmacogenetic polymorphism, which causes deficient detoxification entailing oxidative stress and cell death.
引用
收藏
页码：62 / 63
页数：2
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