A FAMILY HISTORY STUDY OF NEUROPSYCHIATRIC DISORDERS IN THE ADULT SIBLINGS OF AUTISTIC INDIVIDUALS

被引：141
作者：
PIVEN, J
GAYLE, J
CHASE, GA
FINK, B
LANDA, R
WZOREK, MM
FOLSTEIN, SE
机构：
[1] JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT,DIV CHILD PSYCHIAT,BALTIMORE,MD 21205
[2] JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT,DIV PSYCHIAT GENET,BALTIMORE,MD 21205
来源：
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY | 1990年 / 29卷 / 02期
关键词：
affective disorder; autism; cognitive disorder; genetics;
D O I：
10.1097/00004583-199003000-00004
中图分类号：
B844 [发展心理学（人类心理学）];
学科分类号：
040202 ;
摘要：
The family history method was used to obtain developmental, social, and psychiatric histories on the 67 adult siblings of 37 autistic probands. Two of 67 siblings (3.0%) were autistic, three siblings (4.4%) had severe social dysfunction and isolation, 10 (15%) had cognitive disorders, and 10 (15%) had received treatment for affective disorder. This study is the first to investigate the frequency of disorders in the adult siblings of autistic probands. These results suggest aggregation of a variety of neuropsychiatric disorders in the siblings of autistic individuals. © 1990, The American Academy of Child and Adolescent Psychiatry. All rights reserved.
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页码：177 / 183
页数：7
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