A FAMILY HISTORY STUDY OF NEUROPSYCHIATRIC DISORDERS IN THE ADULT SIBLINGS OF AUTISTIC INDIVIDUALS

被引：141

作者：

PIVEN, J

GAYLE, J

CHASE, GA

FINK, B

LANDA, R

WZOREK, MM

FOLSTEIN, SE

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT,DIV CHILD PSYCHIAT,BALTIMORE,MD 21205

[2] JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT,DIV PSYCHIAT GENET,BALTIMORE,MD 21205

来源：

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY | 1990年 / 29卷 / 02期

关键词：

affective disorder; autism; cognitive disorder; genetics;

D O I：

10.1097/00004583-199003000-00004

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

The family history method was used to obtain developmental, social, and psychiatric histories on the 67 adult siblings of 37 autistic probands. Two of 67 siblings (3.0%) were autistic, three siblings (4.4%) had severe social dysfunction and isolation, 10 (15%) had cognitive disorders, and 10 (15%) had received treatment for affective disorder. This study is the first to investigate the frequency of disorders in the adult siblings of autistic probands. These results suggest aggregation of a variety of neuropsychiatric disorders in the siblings of autistic individuals. © 1990, The American Academy of Child and Adolescent Psychiatry. All rights reserved.

引用

页码：177 / 183

页数：7

共 43 条

[1]

American Psychiatric Association, 1980, DIAGN STAT MAN MENT, V3rd

[2]

ANDREASEN NC, 1977, ARCH GEN PSYCHIAT, V34, P1229

[3] The ''autistic psychopathy'' in childhood [J].