Reactivation of Tuberculosis in Three Cases of Psoriasis after Initiation of Anti-TNF Therapy

被引:10
作者
Abu Shaikha, Samya [1 ]
Mansour, Khalid [1 ]
Riad, Hassan [1 ]
机构
[1] Hamad Med Corp, Dept Dermatol, Doha, Qatar
关键词
Psoriasis; Tuberculosis; Biologics; Reactivation;
D O I
10.1159/000337145
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
New biological therapies for disabling diseases such as psoriasis may carry both short- and long-term risks. Tuberculosis (TB) reactivation is a frequent complication of anti-tumor necrosis factor (TNF) therapy. We present 3 cases of psoriasis that were treated with different types of anti-TNF and developed TB infection (TBI) during therapy. One of the cases was diagnosed as active pulmonary TB and the other 2 cases as latent TBI. All cases received appropriate anti-TB treatment, and the anti-TNF therapy was interrupted and then resumed according to various clinical considerations.
引用
收藏
页码:41 / 46
页数:6
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