ARENE OXIDES - NEW ASPECT OF DRUG-METABOLISM

被引:1156
作者
JERINA, DM
DALY, JW
机构
[1] NIAMDD, LAB CHEM, SECT OXIDATION MECHANISM, BETHESDA, MD 20014 USA
[2] NIAMDD, LAB CHEM, SECT PHARMACODYNAM, BETHESDA, MD 20014 USA
关键词
D O I
10.1126/science.185.4151.573
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:573 / 582
页数:10
相关论文
共 144 条
[81]   EVIDENCE OF A GENETIC RELATIONSHIP BETWEEN SUSCEPTIBILITY TO 3-METHYLCHOLANTHRENE-INDUCED SUBCUTANEOUS TUMORS AND INDUCIBILITY OF ARYL HYDROCARBON HYDROXYLASE [J].
KOURI, RE ;
RATRIE, H ;
WHITMIRE, CE .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1973, 51 (01) :197-200
[82]  
KRISHNA G, 1971, PHARMACOLOGIST, V13, P196
[83]  
KUBINSKI H, 1973, CANCER RES, V33, P3103
[84]  
KUROKI T, 1971, CANCER RES, V31, P2168
[85]   BINDING OF K-REGION EPOXIDES AND OTHER DERIVATIVES OF BENZ[A]ANTHRACENE AND DIBENZ[A,H]ANTHRACENE TO DNA, RNA, AND PROTEINS OF TRANSFORMABLE CELLS [J].
KUROKI, T ;
SELKIRK, JK ;
SIMS, P ;
MARQUARDT, H ;
HUBERMAN, E ;
HEIDELBERGER, C ;
GROVER, PL .
CHEMICO-BIOLOGICAL INTERACTIONS, 1972, 4 (06) :389-+
[86]   DETERMINATION OF H-PROTEIN IN TRANSFORMABLE AND TRANSFORMED CELLS IN CULTURE [J].
KUROKI, T ;
HEIDELBERGER, C .
BIOCHEMISTRY, 1972, 11 (11) :2116-+
[87]   ALKYLATION BY PROPYLENE OXIDE OF DEOXYRIBONUCLEIC ACID, ADENINE, GUANOSINE AND DEOXYGUANYLIC ACID [J].
LAWLEY, PD ;
JARMAN, M .
BIOCHEMICAL JOURNAL, 1972, 126 (04) :893-&
[88]   INTERACTION OF NUCLEIC ACIDS .4. PHYSICAL BINDING OF 3,4-BENZPYRENE TO NUCLEOSIDES NUCLEOTIDES NUCLEIC ACIDS AND NUCLEOPROTEIN [J].
LESKO, SA ;
SMITH, A ;
TSO, POP ;
UMANS, RS .
BIOCHEMISTRY, 1968, 7 (01) :434-&
[89]  
LESKO SA, 1971, PROG MOLEC SUBCELL B, V2, P348
[90]   DESTRUCTION OF CYTOCHROME P450 BY SECOBARBITAL AND OTHER BARBITURATES CONTAINING ALLYL GROUPS [J].
LEVIN, W ;
SERNATIN.E ;
JACOBSON, M ;
KUNTZMAN, R .
SCIENCE, 1972, 176 (4041) :1341-&