ARENE OXIDES - NEW ASPECT OF DRUG-METABOLISM

被引：1156
作者：
JERINA, DM
DALY, JW
机构：
[1] NIAMDD, LAB CHEM, SECT OXIDATION MECHANISM, BETHESDA, MD 20014 USA
[2] NIAMDD, LAB CHEM, SECT PHARMACODYNAM, BETHESDA, MD 20014 USA
来源：
SCIENCE | 1974年 / 185卷 / 4151期
关键词：
D O I：
10.1126/science.185.4151.573
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：573 / 582
页数：10
相关论文
共 144 条
[1]   EPOXIDES OF CARCINOGENIC POLYCYCLIC HYDROCARBONS ARE FRAMESHIFT MUTAGENS [J].
AMES, BN ;
SIMS, P ;
GROVER, PL .
SCIENCE, 1972, 176 (4030) :47-&
[2]   POLYCYCLIC HYDROCARBON-PRODUCED TOXICITY, TRANSFORMATION, AND CHROMOSOMAL-ABERRATIONS AS A FUNCTION OF ARYL HYDROCARBON HYDROXYLASE-ACTIVITY IN CELL-CULTURES [J].
BENEDICT, WF ;
NEBERT, DW ;
GIELEN, JE .
INTERNATIONAL JOURNAL OF CANCER, 1972, 9 (02) :435-&
[3]  
BERCHTHOLD GA, UNPUBLISHED RESULTS
[4]   IN VITRO CELL TRANSFORMATION WITH CHEMICAL CARCINOGENS [J].
BERWALD, Y ;
SACHS, L .
NATURE, 1963, 200 (491) :1182-&
[5]   METABOLIC CONVERSION OF BENZO[ALPHA]PYRENE BY SYRIAN-HAMSTER LIVER-MICROSOMES AND BINDING OF METABOLITES TO DEOXYRIBONUCLEIC ACID [J].
BORGEN, A ;
DARVEY, H ;
CASTAGNO.N ;
CROCKER, TT ;
RASMUSSE.RE ;
WANG, IY .
JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (05) :502-506
[6]   HYDROXYLATION OF PHENYLALANINE BY PSEUDOMONAS SP - MEASUREMENT OF AN ISOTOPE-EFFECT FOLLOWING NIH SHIFT [J].
BOWMAN, WR ;
GRETTON, WR ;
KIRBY, GW .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1973, (03) :218-220
[7]   OPTICALLY ACTIVE 1,2-NAPHTHALENE OXIDE [J].
BOYD, DR ;
JERINA, DM ;
DALY, JW .
JOURNAL OF ORGANIC CHEMISTRY, 1970, 35 (09) :3170-&
[8]   REARRANGEMENT OF [1-H-2]-AND [2-H-2]NAPHTHALENE 1,2-OXIDES TO 1-NAPHTHOL - MECHANISM OF NIH SHIFT [J].
BOYD, DR ;
DALY, JW ;
JERINA, DM .
BIOCHEMISTRY, 1972, 11 (10) :1961-&
[9]   METABOLISM OF POLYCYCLIC COMPOUNDS - METABOLISM OF 9,10-EPOXY-9,10-DIHYDROPHENANTHRENE IN RATS [J].
BOYLAND, E ;
SIMS, P .
BIOCHEMICAL JOURNAL, 1965, 95 (03) :788-&
[10]  
BOYLAND E, 1950, BIOCHEM SOC SYMP, V5, P40
12345678910