AN ANTIFUNGAL NAPHTHOQUINONE, XANTHONES AND SECOIRIDOIDS FROM SWERTIA-CALYCINA

被引：51
|
作者：
RODRIGUEZ, S
WOLFENDER, JL
HAKIZAMUNGU, E
HOSTETTMANN, K
机构：
[1] UNIV LAUSANNE,INST PHARMACOGNOSIE & PHYTOCHIM,CH-1015 LAUSANNE,SWITZERLAND
[2] INST RECH SCI & TECHNOL,CURPHAMETRA,BUTARE,RWANDA
来源：
PLANTA MEDICA | 1995年 / 61卷 / 04期
关键词：
D O I：
10.1055/s-2006-958102
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A chemical and biological screening of 25 species of the Gentianaceae family has been undertaken. Both methanolic and dichloromethane extracts of Swertia calycina exhibited a strong antifungal activity against Cladosporium cucumerinum and Candida albicans. The compound responsible for this activity has been isolated and identified as 2-methoxy-1,4-naphthoquinone. It is the first naphthoquinone to be described in Gentianaceae species. LC-UV and LC-TSP-MS analysis of the crude extracts of Swertia calycina also allowed on-line identification of six known xanthones and secoiridoids.
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收藏
页码：362 / 364
页数：3
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