AUTOCRINE MECHANISM FOR V-SIS TRANSFORMATION REQUIRES CELL-SURFACE LOCALIZATION OF INTERNALLY ACTIVATED GROWTH-FACTOR RECEPTORS

被引:125
作者
FLEMING, TP
MATSUI, T
MOLLOY, CJ
ROBBINS, KC
AARONSON, SA
机构
关键词
D O I
10.1073/pnas.86.20.8063
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
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页码:8063 / 8067
页数:5
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共 41 条
[1]   COMPARISON OF BIOLOGICAL PROPERTIES AND TRANSFORMING POTENTIAL OF HUMAN PDGF-A AND PDGF-B CHAINS [J].
BECKMANN, MP ;
BETSHOLTZ, C ;
HELDIN, CH ;
WESTERMARK, B ;
DIMARCO, E ;
DIFIORE, PP ;
ROBBINS, KC ;
AARONSON, SA .
SCIENCE, 1988, 241 (4871) :1346-1349
[2]   INOSITOL TRISPHOSPHATE, A NOVEL 2ND MESSENGER IN CELLULAR SIGNAL TRANSDUCTION [J].
BERRIDGE, MJ ;
IRVINE, RF .
NATURE, 1984, 312 (5992) :315-321
[3]   EFFICIENT REVERSION OF SIMIAN SARCOMA VIRUS-TRANSFORMATION AND INHIBITION OF GROWTH FACTOR-INDUCED MITOGENESIS BY SURAMIN [J].
BETSHOLTZ, C ;
JOHNSSON, A ;
HELDIN, CH ;
WESTERMARK, B .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (17) :6440-6444
[4]   STRUCTURAL ALTERATION OF VIRAL HOMOLOG OF RECEPTOR PROTOONCOGENE FMS AT CARBOXYL TERMINUS [J].
COUSSENS, L ;
VANBEVEREN, C ;
SMITH, D ;
CHEN, E ;
MITCHELL, RL ;
ISACKE, CM ;
VERMA, IM ;
ULLRICH, A .
NATURE, 1986, 320 (6059) :277-280
[5]   BOMBESIN-LIKE PEPTIDES CAN FUNCTION AS AUTOCRINE GROWTH-FACTORS IN HUMAN SMALL-CELL LUNG-CANCER [J].
CUTTITTA, F ;
CARNEY, DN ;
MULSHINE, J ;
MOODY, TW ;
FEDORKO, J ;
FISCHLER, A ;
MINNA, JD .
NATURE, 1985, 316 (6031) :823-826
[6]  
DERYNCK R, 1987, CANCER RES, V47, P707
[7]   OVEREXPRESSION OF THE HUMAN EGF RECEPTOR CONFERS AN EGF-DEPENDENT TRANSFORMED PHENOTYPE TO NIH 3T3 CELLS [J].
DIFIORE, PP ;
PIERCE, JH ;
FLEMING, TP ;
HAZAN, R ;
ULLRICH, A ;
KING, CR ;
SCHLESSINGER, J ;
AARONSON, SA .
CELL, 1987, 51 (06) :1063-1070
[8]   ERBB-2 IS A POTENT ONCOGENE WHEN OVEREXPRESSED IN NIH/3T3 CELLS [J].
DIFIORE, PP ;
PIERCE, JH ;
KRAUS, MH ;
SEGATTO, O ;
KING, CR ;
AARONSON, SA .
SCIENCE, 1987, 237 (4811) :178-182
[9]   SIMIAN SARCOMA-VIRUS ONC GENE, V-SIS, IS DERIVED FROM THE GENE (OR GENES) ENCODING A PLATELET-DERIVED GROWTH-FACTOR [J].
DOOLITTLE, RF ;
HUNKAPILLER, MW ;
HOOD, LE ;
DEVARE, SG ;
ROBBINS, KC ;
AARONSON, SA ;
ANTONIADES, HN .
SCIENCE, 1983, 221 (4607) :275-277
[10]   CLOSE SIMILARITY OF EPIDERMAL GROWTH-FACTOR RECEPTOR AND V-ERB-B ONCOGENE PROTEIN SEQUENCES [J].
DOWNWARD, J ;
YARDEN, Y ;
MAYES, E ;
SCRACE, G ;
TOTTY, N ;
STOCKWELL, P ;
ULLRICH, A ;
SCHLESSINGER, J ;
WATERFIELD, MD .
NATURE, 1984, 307 (5951) :521-527