ALLYLAMINE DERIVATIVES - NEW CLASS OF SYNTHETIC ANTIFUNGAL AGENTS INHIBITING FUNGAL SQUALENE EPOXIDASE

被引：367
作者：
PETRANYI, G
RYDER, NS
STUTZ, A
机构：
[1] SANDOZ FORSCHUNGSINST,DEPT CHEM,A-1235 VIENNA,AUSTRIA
[2] SANDOZ FORSCHUNGSINST,DEPT MOLEC ENZYMOL,A-1235 VIENNA,AUSTRIA
[3] SANDOZ FORSCHUNGSINST,DEPT MYCOL,A-1235 VIENNA,AUSTRIA
来源：
SCIENCE | 1984年 / 224卷 / 4654期
关键词：
D O I：
10.1126/science.6547247
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：1239 / 1241
页数：3
相关论文
共 18 条
[1]   HETEROCYCLIC SPIRO-NAPHTHALENONES .1. SYNTHESIS AND REACTIONS OF SOME SPIRO [(1H-NAPHTHALENONE)-1,3'-PIPERIDINES] [J].
BERNEY, D ;
SCHUH, K .
HELVETICA CHIMICA ACTA, 1978, 61 (04) :1262-1273
[2]   SPECULATIONS ON THE EVOLUTION OF STEROL STRUCTURE AND FUNCTION [J].
BLOCH, KE .
CRC CRITICAL REVIEWS IN BIOCHEMISTRY, 1979, 7 (01) :1-5
[3]  
ELLAMES GJ, 1982, TOPICS ANTIBIOTIC CH, V6, P9
[4]  
GANZINGER U, 1982, CLIN TRIALS J, V19, P342
[5]   INVITRO ACTIVITY OF NAFTIFINE, A NEW ANTIFUNGAL AGENT [J].
GEORGOPOULOS, A ;
PETRANYI, G ;
MIETH, H ;
DREWS, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1981, 19 (03) :386-389
[6]  
HEERES J, ANNU REP MED CHEM, V17, P139
[7]   PURIFICATION AND PARTIAL CHARACTERIZATION OF SQUALENE EPOXIDASE FROM RAT-LIVER MICROSOMES [J].
ONO, T ;
NAKAZONO, K ;
KOSAKA, H .
BIOCHIMICA ET BIOPHYSICA ACTA, 1982, 709 (01) :84-90
[8]  
PETRANYI G, 1982, SABOURAUDIA, V20, P101
[9]   INVIVO ANTI-MYCOTIC ACTIVITY OF NAFTIFINE [J].
PETRANYI, G ;
GEORGOPOULOS, A ;
MIETH, H .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1981, 19 (03) :390-392
[10]  
PETRANYI G, Patent No. 3020113
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