COMPETITION FOR ANTIGEN PRESENTATION IN LIVING CELLS INVOLVES EXCHANGE OF PEPTIDES BOUND BY CLASS-II MHC MOLECULES

被引：106

作者：

ADORINI, L

APPELLA, E

DORIA, G

CARDINAUX, F

NAGY, ZA

机构：

[1] NCI,CELL BIOL LAB,BETHESDA,MD 20892

[2] CRE CASACCIA,ENERGIA NUCL & ENERGIA ALTERNAT,PATHOL LAB,I-00100 ROME,ITALY

来源：

NATURE | 1989年 / 342卷 / 6251期

关键词：

D O I：

10.1038/342800a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：800 / 803

页数：4

共 14 条

[1] INTERACTION OF AN IMMUNODOMINANT EPITOPE WITH IA MOLECULES IN T-CELL ACTIVATION [J].

ADORINI, L ;

SETTE, A ;

BUUS, S ;

GREY, HM ;

DARSLEY, M ;

LEHMANN, PV ;

DORIA, G ;

NAGY, ZA ;

APPELLA, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (14) :5181-5185

[2] MECHANISMS INFLUENCING THE IMMUNODOMINANCE OF T-CELL DETERMINANTS [J].

ADORINI, L ;

APPELLA, E ;

DORIA, G ;

NAGY, ZA .

JOURNAL OF EXPERIMENTAL MEDICINE, 1988, 168 (06) :2091-2104

[3] BINDING OF IMMUNOGENIC PEPTIDES TO IA HISTOCOMPATIBILITY MOLECULES [J].

BABBITT, BP ;

ALLEN, PM ;

MATSUEDA, G ;

HABER, E ;

UNANUE, ER .

NATURE, 1985, 317 (6035) :359-361

[4] ISOLATION AND CHARACTERIZATION OF ANTIGEN-IA COMPLEXES INVOLVED IN T-CELL RECOGNITION [J].

BUUS, S ;

SETTE, A ;

COLON, SM ;

JENIS, DM ;

GREY, HM .

CELL, 1986, 47 (06) :1071-1077

[5] INTRACELLULAR CLASS-II HLA ANTIGENS ARE ACCESSIBLE TO TRANSFERRIN NEURAMINIDASE CONJUGATES INTERNALIZED BY RECEPTOR-MEDIATED ENDOCYTOSIS [J].

CRESSWELL, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (23) :8188-8192

[6] TRANSGLUTAMINASE IS ESSENTIAL IN RECEPTOR-MEDIATED ENDOCYTOSIS OF ALPHA-2-MACROGLOBULIN AND POLYPEPTIDE HORMONES [J].

DAVIES, PJA ;

DAVIES, DR ;

LEVITZKI, A ;

MAXFIELD, FR ;

MILHAUD, P ;

WILLINGHAM, MC ;

PASTAN, IH .

NATURE, 1980, 283 (5743) :162-167

[7] LYSOSOMOTROPIC AGENTS [J].

DEDUVE, C ;

DEBARSY, T ;

POOLE, B ;

TROUET, A ;

TULKENS, P ;

VANHOOF, F .

BIOCHEMICAL PHARMACOLOGY, 1974, 23 (18) :2495-+

[8] TURNOVER OF IA PEPTIDE COMPLEXES IS FACILITATED IN VIABLE ANTIGEN-PRESENTING CELLS - BIOSYNTHETIC TURNOVER OF IA VS PEPTIDE EXCHANGE [J].

HARDING, CV ;

ROOF, RW ;

UNANUE, ER .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (11) :4230-4234

[9] ACIDIFICATION OF THE ENDOCYTIC AND EXOCYTIC PATHWAYS [J].

MELLMAN, I ;

FUCHS, R ;

HELENIUS, A .

ANNUAL REVIEW OF BIOCHEMISTRY, 1986, 55 :663-700

[10]

Moller G., 1987, IMMUNOL REV, V98, P1

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