STERIC CONSTRAINTS IN INTRAMOLECULAR REACTIONS AT SP-3 CARBON IMPLICATIONS FOR METHYLASE MECHANISMS

被引：15

作者：

LOK, R ^{[1
]}

COWARD, JK ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,DEPT PHARMACOL,NEW HAVEN,CT 06510

来源：

BIOORGANIC CHEMISTRY | 1976年 / 5卷 / 02期

关键词：

D O I：

10.1016/0045-2068(76)90005-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：169 / 175

页数：7

共 18 条

[1] ARYLTRIALKOXYSULFURANE PREPARED FROM A CYCLIC SULFENATE - POLARITY RULES AND SULFURANE REACTIVITY [J].

ASTROLOGES, GW ;

MARTIN, JC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (23) :6909-6911

[2] AFFINITY LABELING OF CATECHOL O-METHYLTRANSFERASE BY N-HALOACETYL DERIVATIVES OF 3,5-DIMETHOXY-4-HYDROXYPHENYLETHYLAMINE AND 3,4-DIMETHOXY-5-HYDROXYPHENYLETHYLAMINE - KINETICS OF INACTIVATION [J].

BORCHARDT, RT ;

THAKKER, DR .

BIOCHEMISTRY, 1975, 14 (20) :4543-4551

[3] GENERAL BASE CATALYSIS IN NUCLEOPHILIC-ATTACK AT SP3 CARBON OF METHYLASE MODEL COMPOUNDS [J].

COWARD, JK ;

LOK, R ;

TAKAGI, O .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (04) :1057-1059

[4] CLEAVAGE OF N-CARBOBENZYLOXY GROUP IN NEUTRAL AND BASIC MEDIA - NEIGHBORING-GROUP PARTICIPATION OF CARBAMATE MOIETY [J].

COWARD, JK ;

LOK, R .

JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (14) :2546-2548

[5] KINETIC STUDIES ON CATECHOL O-METHYLTRANSFERASE - PRODUCT INHIBITION AND NATURE OF CATECHOL BINDING-SITE [J].

COWARD, JK ;

SLISZ, EP ;

WU, FYH .

BIOCHEMISTRY, 1973, 12 (12) :2291-2297

[6] KINETICS AND MECHANISM OF METHYL TRANSFER FROM SULFONIUM COMPOUNDS TO VARIOUS NUCLEOPHILES [J].

COWARD, JK ;

SWEET, WD .

JOURNAL OF ORGANIC CHEMISTRY, 1971, 36 (16) :2337-&

[7]

CREVELING CR, 1972, MOL PHARMACOL, V8, P398

[8]

JENCKS WP, 1969, CATALYSIS CHEMISTRY, P283

[9] OXIDATION OF SULFIDES WITH T-BUTYL HYPOCHLORITE . EVIDENCE FOR A TETRACOVALENT SULFUR INTERMEDIATE [J].

JOHNSON, CR ;

RIGAU, JJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (19) :5398-&

[10] MECHANISM OF ALKALINE DECOMPOSITION OF TRIARYLSULFONIUM BROMIDE WITH PHENYLLITHIUM [J].

KHIM, YH ;

OAE, S .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1969, 42 (07) :1968-+

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