OSTEOPOROSIS IN SEVERE CONGENITAL NEUTROPENIA TREATED WITH GRANULOCYTE-COLONY-STIMULATING FACTOR

被引：0

作者：

BISHOP, NJ

WILLIAMS, DM

COMPSTON, JC

STIRLING, DM

PRENTICE, A

机构：

[1] UNIV CAMBRIDGE,DEPT PEDIAT,CAMBRIDGE,ENGLAND

[2] UNIV CAMBRIDGE,DEPT MED,CAMBRIDGE,ENGLAND

[3] UNIV CAMBRIDGE,MRC,DUNN NUTR UNIT,CAMBRIDGE,ENGLAND

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 1995年 / 89卷 / 04期

关键词：

SEVERE CONGENITAL NEUTROPENIA; G-CSF; OSTEOPOROSIS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recombinant human granulocyte colony-stimulating factor (G-CSF) has substantially improved life expectancy for children with severe congenital neutropenia (SCN). Severe osteoporosis, reported in this population, may relate to the disease process, or be a therapeutic side-effect. This report details bone loss, quantitated absorptiometrically and histomorphometrically, in a child with SCN and vertebral collapse, and the positive response to anabolic steroid and bisphosphonate therapy.

引用

页码：927 / 928

页数：2

共 8 条

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